RT Journal Article
SR Electronic
T1 Changes of the pulmonary arteries in patient with pulmonary hypertension: Using optical coherence tomography
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p3693
VO 38
IS Suppl 55
A1 Elena Belyatko
A1 N. Danilov
A1 Y. Machin
A1 I. Chazova
A1 I. Chazova
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p3693.abstract
AB Objective: To assess clinical using of optical coherence tomography (OCT) in patient with pulmonary artery hypertension (PAH).Design and method: We studied the condition of vessels in a patient with systemic scleroderma and PAH. Our patient was a woman of 57 years. In the study, we used the following equipment specifications: IVUS (Eagle Eye Gold, catheter 40 MHz; Inc., USA), OCT (Light Lab Imaging Inc.) and general characteristics of different tissues by OCT.Results: Cardiac catheterization showed pulmonary artery pressure of 90/20/35 mm Hg. Pulmonary capillary wedge pressure - 9 mm Hg. Both IVUS and OCT visualized the anterior basal segment pulmonary artery at the level of 16,3 mm2 (external area) by IVUS and at the level of 16,15 mm2 by OCT. Intima thickness was 0,41 mm by IVUS and 0,68 by OCT. We analyzed the tissue characteristics of the segment by OCT. We didn't find the scarp borderers, irregular borders or superficial signal. Thus we didn't find any features of calcium, lipids or mural thrombosis. The predominant tissue of the defected segment was homogenous bright tissue, e.t. fibrosis. We attempted to use radiofrequent analysis (VH by IVUS), but, because of its lower resolution in the case of pulmonary arteries, in comparison to the coronary arteries, it turned poor information.Conclusions: In the case of PAH IVUS looks like a method, which underestimates the intima thickness, in comparison with OCT. OCT enables to detect morphological features and possible injures of the inner layer of the vessel wall. However, like any new technology, OCT will require a learning curve, to improve our ability and optimize treatment of patients with PAH.