TY - JOUR T1 - Health-related quality of life in non-cystic fibrosis bronchiectasis children JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p4573 AU - Ameer Hamzah AU - Yasemin Gokdemir AU - Cagatay Cimsit AU - Refika Ersu AU - Fazilet Karakoc AU - Bulent Karadag Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p4573.abstract N2 - Aim: Bronchiectasis is still an important problem in developing countries. The aim of this study was to evaluate the health-related quality of life and associated factors in children with non-cystic fibrosis bronchiectasis.Method: Children with non–cystic fibrosis bronchiectasis followed at Marmara University Paediatric Pulmonology Clinic were included to the study. Age of symptom onset, age of diagnosis, frequency of presenting symptoms, physical examination findings, pulmonary function tests, and affected lobes in high resolution computed tomography (HRCT) were evaluated; in addition, HRCT was scored according to modified Bhalla score system to obtain a bronchiectasis distribution severity score. St George's Respiratory Questionnaire (SGRQ) and the Medical Outcomes Study Short Form-36 were completed by patients and parents.Results: The median age of the patients (48.9% male) was 12.1 years (25%-75% 10.2-14.1years). The median age at diagnosis was 7 years (25%-75% 5-10years) and follow up period was 4 years (25%-75% 2-5 years). The patients' HRCT score did not correlate with the SGRQ score and FEV1 (p>0.05). However, a significant correlation was found between the SGRQ scores and FEV1 (p<0.05).No correlation was found between SF-36 and FEV1 (p>0.05).Conclusion: Patients with worse pulmonary functions have lower quality of life scores. Early diagnosis and treatment may increase the quality of life and survival of patients with bronchiectasis, which has irreversible and progressive complications if untreated. ER -