PT  - JOURNAL ARTICLE
AU  - J.K. Samaria
AU  - Hemant Kumar
TI  - pH – and serum sodium level as an important predictor of mortality in acute exacerbation of COPD
DP  - 2011 Sep 01
TA  - European Respiratory Journal
PG  - p2053
VI  - 38
IP  - Suppl 55
4099  - http://erj.ersjournals.com/content/38/Suppl_55/p2053.short
4100  - http://erj.ersjournals.com/content/38/Suppl_55/p2053.full
SO  - Eur Respir J2011 Sep 01; 38
AB  - Background: AECOPD result in increased morbidity and mortality, and constitute a tremendous socioeconomic burden. Predicting in-hospital mortality may aid prognostication and plan for future therapies.Aim of study: Predicting in-hospital mortality in patient of Acute Exacerbation of COPD help in planning the course of future treatment for averting the impending morbidity and mortality.Methods: Study includes 94 patients of Acute Exacerbation of COPD admitted in the Tertiary Care Hospital were subjected to thorough history and clinical examination, all relevant examinations including ABG & others like RFT, LFT, CBC, RBC etc were done. All the patients of AECOPD managed either by NIV or given invasive ventilation in ICU.Results: Most patients were elderly with mean age of 62.3 years. Mortality rate was 17% (16/94) during hospital stay. Mean pH of the patients 7.382 (SD=0.0878). pH of those patients who expired were mean 7.3035 (SD 0.111) and patients who survived were mean 7.3989 (SD 0.706). The difference was significant (P=0.003) (CI 0.33855 – 0.156935). Sodium level of the patients in the study were 133.93 (SD 8.481), patients who expired the sodium level were mean 123.43 (SD 11.267) and those who survived mean sodium were 135.92 (SD 6.264). The difference was significant (P=0.001) (CI=6.505 – 18.475).Conclusion: pH and serum sodium level at the time of admission are independent predictors of mortality in patients with Acute Exacerbation of COPD.