RT Journal Article SR Electronic T1 Prevalence and pattern of pulmonary infections among HIV/AIDS adults patients admitted to a tertiary care hospital, Dubai, United Arab Emirates, 2009-2010 JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP p2529 VO 38 IS Suppl 55 A1 Layla Al-Dabal A1 Samar Badreddin A1 Ali Abro A1 Nadeem Younis Javeed YR 2011 UL http://erj.ersjournals.com/content/38/Suppl_55/p2529.abstract AB Background: The prevalence of HIV in UAE in estimated to be < 0.2% among adults and there is no data on pulmonary complications of HIV/AIDS. The study was aimed to evaluate the prevalence and pattern of pulmonary infections among HIV/AIDS infected patients over 2 years period.Methods: Data was collected longitudinally as patients were admitted to IDU and included demographics, CD4, viral load, chest X-Ray, sputum microscopy/culture, AFB staining/culture and first line DST. CT chest and FOB were used in few selected cases.Results: Between January 2009 and January 2011, 97 adult patients with HIV/AIDS were admitted to our unit. 45 patients had abnormal chest X-ray and non specific respiratory symptoms (46.39%), mostly presenting with cough (93%). We identified 19/45 (42.2%) patients with active pulmonary TB, 14/45 (31.1%) patients with CAP and 4/45 (8.8%) patients with PJP. No confirmed diagnosis was made in 8/45 (17.7%) patients, out of whom 6 patients died within 48-72 hours of admission. No patient was receiving ART or prophylaxis at the time of pulmonary infection. 29/45 patients had CD4 <200/μL (70.73%, range 3-193), and 13 patients had CD4 > 200/μL (31.7%, range 248-579). 14/18 (77.7%) patients with pulmonary tuberculosis had CD < 200/μL with chest X –ray changes consistent with primary infection. The rate of sputum slide/culture positivity was 78.5% and 92.8% respectively.Conclusions: Pulmonary TB was most frequently diagnosed illness followed by CAP. In patients with AIDS and TB, chest x ray shows a pattern of primary infection and sputum positivity was comparable to HIV infected and immunocompetent subjects.