%0 Journal Article %A Stefhanie Nayar %A Ana MarĂ­a Escobar %A Monica Saavedra %A Alberto Vidal %T Pulmonary function and quality of life in children and adolescents adenovirus bronchiolitis obliterans %D 2011 %J European Respiratory Journal %P p4568 %V 38 %N Suppl 55 %X Introduction: There are few studies assessing pulmonary function and quality of life of PIBO patients.Objective: Assess the pulmonary function and the quality of life of patients with PIBO and the correlation between both variables.Methods: 14 Children with PIBO in follow up at the pediatric pulmonology, were included in this study. Study period: April 2009 - April 2010. Pulmonary function was assessed with spirometry, flow/volume curve and intrathoracic gas volume. A survey of self-administered Quality of Life was applied at the visit to investigate their global, physical and psychosocial quality of life. The Pearson linear correlation between quality of life and the pulmonary function test parameters was assessed, for statistical analysis p<0.05 was considered significant.Results: The mean age of our patients was 12.4. The functional alterations were characteristics of an obstructive respiratory disorder in 85.7% and only 14.3% showed normal pulmonary functionof the patients. The quality of life parameters were in average 58.6% of overall quality of life, 60.9% of physical quality of life and 57.9% of psychosocial quality of life. We found a positive correlation between global quality of life and VEF1, FVC and FEF25-75% (correlation index 0.54, 0.53 and 0.53 respectively) as well between physical quality of life and VEF1, FVC, FEV1/FVC and FEF25-75% (correlation index 0.86, 0.81, 0.70 and 0.74 respectively).Conclusions: Most patients with PIBO showed pulmonary function impairment characterized by an obstructive respiratory pattern. Better quality of life correlates with better values in spirometric parameters. %U