TY - JOUR T1 - Specific pulmonary lesion in patients with tubercular spondylitis (TS) JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p2678 AU - Viacheslav Zhuravlev AU - Galina Vasilieva AU - Pavel Gavrilov Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p2678.abstract N2 - 120 patients with active pulmonary tuberculosis (PT) and diagnosis of TS were studied. It was the patients at the age from 18 to 72 years old. The patients were examined due to complaints of spinal pain. These were mostly the lesions of thoracic spine 46 (38,3%). From 2 to 8 vertebras were affected, dissiminated forms were diagnosed in 62 (51,6%) patients. In 113 (94,2%) the TS was complicated with paravertebral abscesses, in 92 patients (76,6%) – with epidural abscesses, in 49 (40,8%) - neurological disorders were diagnosed. 62 (51,7%) had simultaneously diagnosed PT and spine lesion, in 58 (48,3%) the TS was diagnosed in 2,5±1,8 years after beginning of PT therapy. Clinical forms of PT: disseminated 44 (36,7%), infiltrative 38 (31,7%), fibrocavitary 22 (18,3%), tuberculosis of intrathoracic lymph nodes 10 (8,3%), focal 6 (5,0%). Pulmonary tissue destruction was diagnosed in 83% of cases. Mycobacteria tuberculosis (MBT) were identified in respiratory material of 95 (79,2%) patients. Multiple drug resistance of MBT was diagnosed in 73 (60,8%) patients. All patients required surgical treatment of TS. The intensive chemotherapy during 4,5±2,1 months, positive clinical and x-ray dynamics and negative results of bacterioscopic examination of sputum for MBT detection has helped to carry out surgical stage of treatment in 115 patients. 5 (4,2%) patients had no surgical treatment of TS because of advance of the generalized tuberculosis.Conclusion: In case of detection of associated affection of PT and TS it is necessary to carry out not less than 2 months of intensive therapy using 5 antituberculous drugs, with further surgical stage at the affected spine part and continuation of specific therapy for not less than 6 months. ER -