PT - JOURNAL ARTICLE AU - Sofia Granadeiro AU - Alexandra Borba AU - Luisa Semedo AU - Miguel Araujo AU - João Cardoso AU - Fernando Martelo AU - Jose Fragata TI - Characterization of a population referred to a lung transplantation centre in Lisbon DP - 2011 Sep 01 TA - European Respiratory Journal PG - p2455 VI - 38 IP - Suppl 55 4099 - http://erj.ersjournals.com/content/38/Suppl_55/p2455.short 4100 - http://erj.ersjournals.com/content/38/Suppl_55/p2455.full SO - Eur Respir J2011 Sep 01; 38 AB - Introduction: Lung transplantation is the therapeutic option for patients with end stage lung disease. An appropriate referral contributes to a better post surgery survival.Purpose: Characterization of the patients referred to the only lung transplantation centre in Portugal.Material and method: The authors evaluated patients referred from January 2008 to December 2010. The following data was determined: demographics, lung disease and evaluation result. Reasons for refusal were also analyzed.Results: A total of 199 patients were referred (61% male), with an medium age of 45,5 years (range 11 to 69). Thirty per cent had the diagnosis of terminal lung fibrosis, 21% COPD, 13% cystic fibrosis, 12% bronchiectasis and the last 23% other diagnosis. After evaluation 24,6% of patients were accepted (49 patients, 25 of which already transplanted and 5 died on waiting list) and 54,3% were refused, most due to severe cardiac impairment or very poor general condition. Of the remaining patients, 9,5% are under current evaluation, 6,5% present a relative contraindication and 5% still don't meet criteria for transplantation.Conclusion: Despite the considerable number of patients referred, only 45,7% were eligible for lung transplant. The important number of patients refused due to medical contraindications should alert the attending physicians for an earlier referral.