TY - JOUR T1 - Sleep apnea symptoms in diabetics and their first degree relatives JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p3051 AU - Babak Amera AU - Farideh Sheikh Bahaee AU - Masoud Amini AU - Mohammad Golshan AU - Ingo Fietze AU - Thomas Penzel Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p3051.abstract N2 - Background: The purpose of our study was to investigate high risk for sleep apnea syndrome, in a cohort of diabetics and their first degree relatives with different categories of serum glucose level: diabetic, impaired glucose tolerance (IGT), and normal glucose.Methods: As a part of a cohort study, all of diabetic and their first degree relatives who came for glucose control in diabetes clinic, were invited to take part in the survey. 2,462 individuals (82%) agreed to fill out the Berlin and Epworth sleep questionnaire. Participants consisted of 2462 subjects 15–70 years of age, both males and females With diabetes and family history of type 2 diabetes mellitus. A total of 1232 (50.1%) participants had diabetes, 568 (23.1%) abnormal glucose tolerance test, and 662 (26.8%) normal glucose. High risk for sleep apnea regarding Berlin questionnaire and Epworth sleepiness scale, diabetic, impaired glucose tolerance and relative with normal glucose were analyzed.Results: Prevalences of high risk for sleep apnea were lowest in first degree relatives with normal glucose group (30.6%) and highest among diabetics (50.5%). In a multiple regression analysis, “age, BMI, education, high blood pressure” were risk factor for sleep apnea symptoms while isolated blood glucose level was not by Berlin questionnaire. By Epworth sleep scale only education level was a risk factor for sleep apnea symptoms while isolated blood glucose level was not risk factor.Conclusions: Sleep apnea symptoms are common in first degree relatives of diabetic patients regardless of blood glucose level. Level of blood glucose in Groups with diabetes and abnormal GTT and family of diabetic could not affect sleep apnea symptoms. ER -