TY - JOUR T1 - The King's brief interstitial lung disease quality of life questionnaire (K-BILD) for patients with IPF and other ILDs JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - 4863 AU - Amit S. Patel AU - Richard Siegert AU - Kate Brignall AU - Sabrina Bhajwah AU - Sujal R. Desai AU - Athol U. Wells AU - Irene J. Higginson AU - Surinder S. Birring Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/4863.abstract N2 - We set out to develop a brief ILD specific health related quality of life (HRQOL) questionnaire for patients with idiopathic pulmonary fibrosis (IPF) and other ILDs. Items were generated from patient interviews (n=10), literature review and a multi-disciplinary team meeting. A preliminary questionnaire consisting of 71 items and a 7 point Likert response scale was tested in 173 patients (49 IPF). The following items were removed: 1) floor effect: >60% of participants responded “rare” or “never” (25 items), 2) inter-item correlations of r>0.8 (7 items), 3) Exploratory factor analysis (FA): items loading <0.5 on each factor (5 items). A scree plot suggested a 4 factor solution. 4) Items that did not fit unidimensional scales following Rasch analysis (9 items). The remaining 25 items were pooled together and subjected to further Rasch analysis to eliminate items that did not conform to a unidimensional overall HRQOL scale (10 items removed). A repeat FA was performed to confirm the remaining items conformed to the original factor solution. The fourth factor consisted of 1 item which was considered too small to constitute a health domain but remained in the questionnaire to generate an overall HRQOL score. The final King's Brief ILD questionnaire (K-BILD) comprises of 15 items which generate an overall and 3 health domain QOL scores (Psychological (7items), Breathlessness and Activities (4 items) and Physical Symptoms (3 items). The K-BILD is currently undergoing evaluation of repeatability and responsiveness. ER -