RT Journal Article
SR Electronic
T1 The King's brief interstitial lung disease quality of life questionnaire (K-BILD) for patients with IPF and other ILDs
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 4863
VO 38
IS Suppl 55
A1 Amit S. Patel
A1 Richard Siegert
A1 Kate Brignall
A1 Sabrina Bhajwah
A1 Sujal R. Desai
A1 Athol U. Wells
A1 Irene J. Higginson
A1 Surinder S. Birring
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/4863.abstract
AB We set out to develop a brief ILD specific health related quality of life (HRQOL) questionnaire for patients with idiopathic pulmonary fibrosis (IPF) and other ILDs. Items were generated from patient interviews (n=10), literature review and a multi-disciplinary team meeting. A preliminary questionnaire consisting of 71 items and a 7 point Likert response scale was tested in 173 patients (49 IPF). The following items were removed: 1) floor effect: >60% of participants responded “rare” or “never” (25 items), 2) inter-item correlations of r>0.8 (7 items), 3) Exploratory factor analysis (FA): items loading <0.5 on each factor (5 items). A scree plot suggested a 4 factor solution. 4) Items that did not fit unidimensional scales following Rasch analysis (9 items). The remaining 25 items were pooled together and subjected to further Rasch analysis to eliminate items that did not conform to a unidimensional overall HRQOL scale (10 items removed). A repeat FA was performed to confirm the remaining items conformed to the original factor solution. The fourth factor consisted of 1 item which was considered too small to constitute a health domain but remained in the questionnaire to generate an overall HRQOL score. The final King's Brief ILD questionnaire (K-BILD) comprises of 15 items which generate an overall and 3 health domain QOL scores (Psychological (7items), Breathlessness and Activities (4 items) and Physical Symptoms (3 items). The K-BILD is currently undergoing evaluation of repeatability and responsiveness.