@article {Jungp942, author = {Seung Wook Jung and Yeon Jae Kim and Byung Ki Lee and Shin Yup Lee and Chi Young Jung and Kyung Chan Kim and Dae Sung Hyun}, title = {30 cases of tracheobronchopathia osteochondroplastica: Multicenter analysis}, volume = {38}, number = {Suppl 55}, elocation-id = {p942}, year = {2011}, publisher = {European Respiratory Society}, abstract = {Background: Tracheobronchopathia osteochondroplastica (TBO) is a rare benign disease characterized by multiple submucosal osteocartilaginous nodules of trachea and bronchi. However, data concerning TBO patients are limited in korea.Methods: From 2005 through 2010, a retrospective study was conducted in 30 TBO patients recruited from 4 hospitals (3 university faciliated hospitals and 1 community hospital) in korea. The baseline characteristics, clinical presentations, radiographic features, bronchoscopic findings and clinical outcomes in these patients were reviewed.Results: Among the 14,267 patients with flexible fiberoptic bronchoscopy, 30 patients (0.2\%) were diagnosed with TBO. Patients were composed of 17 male and 13 female with a mean age of 60 years. The common symptoms were cough, dyspnea, and hemoptysis. Endotracheal nodules were the most common findig on computed tomography (CT). Osteocartilaginous nodules were mainly present in trachea on bronchoscopy, and the most common type was confluent form. The mean FEV1 was 101\%predicted. Treatment included mostly conservative (n = 29) and then symptoms were considerably relieved in 8 cases but there was no significant improvement noted in 18 patients. 4 patients died on account of associated lung lesion.Conclusion: In accordance with previous studies, TBO is a rare disease and the diagnosis should be suspected based on CT findings and bronchoscopic examination of the airways. This study demonstrated that conservative treatment according to clinical symptom was effective and showed relatively good clinical outcome.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/38/Suppl_55/p942}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }