PT  - JOURNAL ARTICLE
AU  - Beatriz Arias Arcos
AU  - Ascensiόn Hernando Sanz
AU  - Fernando Gonzalez Torralba
AU  - Salvador De la Torre Carazo
AU  - Trinidad Díaz Cambriles
AU  - Maria Josefa Díaz de Atauri Rodriguez de los Ríos
TI  - SAHS and stroke. CPAP compliance and new stroke events
DP  - 2011 Sep 01
TA  - European Respiratory Journal
PG  - p1749
VI  - 38
IP  - Suppl 55
4099  - http://erj.ersjournals.com/content/38/Suppl_55/p1749.short
4100  - http://erj.ersjournals.com/content/38/Suppl_55/p1749.full
SO  - Eur Respir J2011 Sep 01; 38
AB  - Aim: To describe CPAP compliance and new ischemic stroke events in SAHS post stroke patients.Methods and participants: Prospective observational study. Inclusion criteria: patients suffered from stroke event from January 2000 until November 2010 and posterior SAHS diagnosis with 3 months follow up. Two groups were defined: group 1, patients with current CPAP use and group 2, patients with no CPAP treatment. All were evaluated for new stroke events. SAHS, was defined as AHI (apnea + hypopnea per hour of sleep/recording) ≥ 10 and severe as AHI >30. Bivariate analysis was performed to evaluate differences between groups, and multivariate of COX proportional risks to review new stroke and variables as sex, age, BMI, neck circumference, Epworth scale, ODI,% time saturation under 90%, AIH, cigarette smoking and hypertension.Results: 110 patients were included, 85 men (77%), mean age 62±10.7 SD. Group 1 and group 2 were 62 and 48 patients, respectively. New events incidence in group 1 was 16 (26%) and 11 (23%) in group 2, they were no significant statistic differences (p=0.72). The statistically significant variables in multivariate analysis were neck circumference OR [0.87 (IC95% 0.76-0.99; p=0.04)] and BMI OR [0.86 (IC95% 0.75-0.98; p=0.02)]. The survival analysis results are:View this table:The stroke event free time until new event in group 1 was 31.4 months ± 22.6 SD, and in group 2, 25.32 months ±13.9 SD, without statistical significance.Conclusions: New stroke development is not associated with CPAP compliance, however it seems to have longer survival probability in CPAP compliant patients.