PT - JOURNAL ARTICLE AU - Francois Vermeulen AU - Inge Muylle AU - Isabelle De Meulder AU - Marie Bruyneel AU - Vincent Ninane TI - Level of agreement between five asthma control questionnaires DP - 2011 Sep 01 TA - European Respiratory Journal PG - p1296 VI - 38 IP - Suppl 55 4099 - http://erj.ersjournals.com/content/38/Suppl_55/p1296.short 4100 - http://erj.ersjournals.com/content/38/Suppl_55/p1296.full SO - Eur Respir J2011 Sep 01; 38 AB - Introduction: The Global Initiative for Asthma (GINA) guideline outlines the importance of a total control of asthma. This control is assessed by questionnaires evaluating symptoms, reliever use and functional results. We have assessed 5 different questionnaires and evaluated the degree of agreement between them.Methods: Successive asthma patients with a more than 3 months diagnosis were recruited at our out-patient clinic. They were asked to complete consecutively 5 asthma control questionnaires (GINA, ACQ, ACT, ATAQ, RCP) in a random order. Spirometry and exhaled nitric oxide were also measured. The GINA score was considered as the reference test and compared to the four others using the kappa statistic. For comparison with the ACT and RCP questionnaire, the “partly controlled” level GINA questionnaire was considered as “uncontrolled”.Results: Eighty patients (1.61 female for 1 male) aged 41.8±16.7 years-old were recruited between June and December 2010. The GINA questionnaire results agreed with the ACQ in 62.5% of cases (controlled 22.5%, party controlled 12.5%, uncontrolled 27.5% - kappa 0.44, p<0.001), with the ACT in 62.5% of cases (controlled 25.0%, uncontrolled 47.5% - kappa 0.46, p<0.001), with the ATAQ in 45.1% of cases (controlled 26.3%, partly controlled 17.5%, uncontrolled 18.8% - kappa 0.45, p<0.001), and with the RCP in 81.3% of cases (controlled 18.8%, uncontrolled 62.5% - kappa 0.54, p<0.001).Conclusion: Despite the fact that most of these questionnaires have been validated, the agreement between them was moderate. The shortest questionnaire (RCP) showed the highest level of agreement with GINA.