RT Journal Article
SR Electronic
T1 Modification of the international primary care airways group (IPAG)-questionnaire for Japanese
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p4219
VO 38
IS Suppl 55
A1 Go Tsukuya
A1 Takuya Samukawa
A1 Tsutomu Hamada
A1 Kaoru Oketani
A1 Masatada Soejima
A1 Hiroyuki Nagahama
A1 Hirohito Tsubouchi
A1 Hiromasa Inoue
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p4219.abstract
AB Background: Several reports showed the IPAG- Questionnaire (Q) is useful for screening COPD, but may require modification for Japanese. However its modification hasn't been reported yet.Objective: The aim of this study was to establish a modified IPAG-Q for Japanese.Method: Smokers (excepting those with a history of bronchial asthma) aged 40 and over who underwent a screening CT and had given written informed consent were enrolled. They were classified into two groups based on the results of respiratory function tests (FEV1% ≥ or < 70%): control-smokers and a COPD group. We compared the original IPAG-Q between the two groups and statistically analyzed the results to modify it.Results: A total of 268 subjects (control-smokers/COPD: 244/24) were enrolled. We described the receiver operating characteristic (ROC) curve about the original IPAG-Q: the area under the ROC curve (AUC) was 0.764, cut-off was 18.5/total 56 (score), sensitivity was 0.750 and specificity was 0.615. Logistic regression analysis revealed only “wheeze frequency” was useful in the “symptoms/history”, so we deleted “symptoms/history” except for this parameter. And we improved the stratification for age, BMI, and pack/year: age ≥ or < 50 yrs, BMI <18.5/≥ 18.5 & < 25.0/≥ 25.0, and pack/year ≥ or < 30. We then constructed a new scoring system based on the original paper and designed a modified IPAG-Q for Japanese. This modified model was proved valid in the ROC curve; AUC was 0.828, cut-off was 8.5/total 31 (score), sensitivity was 0.833 and specificity was 0.672. This model was superior to the original one.Conclusion: Our modified IPAG-Q is of greater use for screening COPD among Japanese than the original one.