TY - JOUR T1 - Prevalence, relation to smoking and other factors of COPD: Evidence from population survey JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p4142 AU - Marine Gambaryan AU - Anna Kalinina AU - Svetlana Shalnova AU - Alexander Deev AU - Alexander Popugaev AU - Emilia Volkova AU - Kundul Ivanov Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p4142.abstract N2 - Although COPD is a leading cause of worldwide disability and mortality it remains greatly underestimated in primary health care in Russia.The aim of this study is to provide estimates of the prevalence of COPD in Russia in relation to patterns of cigarette smoking and environmental conditions.Methods: Subjects aged 35-64 (N=3771; RR=81%) randomly selected participants from multi-centre population based epidemiological study in three Russian regions with different environmental conditions were included in the analysis. Chi-squared tests and odds ratios (OR) were utilized; multiple logistic regression was employed to analyze association between COPD and smoking patterns and environmental conditions.Results: COPD was revealed in 12.9% of men and 15.7% of women, whereas only 50.9% of those were ever told to have any respiratory diagnosis (p<0.001). COPD is strongly related to smoking intensity. It is 10.5 times more likely to be related to heavy smoking in men (OR=10.5; 95%CI 5.4-19.2) and 5 times women: (OR=5; 95%CI 2.8-8.8), but also with moderate smoking (OR=4.4, 2.9-6.7) and (OR=2.6,1.8-3.8), low (OR=2.6, 1.8-3.8) and even ex-smoking:(OR=3.06, 1.9-4.9) with short quitting history. No significant relation to intention to quit revealed.Significant relations of COPD to environmental conditions are observed: with strongest relationships to region with severe climate conditions in Russian Far East close to Polar Circle:(OR=2.9, 95%CI 2.2-3.9), and Heavy Industrial region: (OR=2.2, 1.6-3.0).Conclusion: COPD is common among adults in Russia and is mainly undiagnosed. It is strongly associated to smoking and higher cigarette consumption, but also to living area which requires further investigation. ER -