RT Journal Article
SR Electronic
T1 Medical pleurodesis – Safety, effectiveness and adherence to the guidelines: East of England DGH experience
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP p2825
VO 38
IS Suppl 55
A1 Azhar Jahangir
A1 Venu Sirpa
A1 Arun Arya
A1 Subramani Durairaj
YR 2011
UL http://erj.ersjournals.com/content/38/Suppl_55/p2825.abstract
AB The aim of the study was to review the safety and effectiveness of medical pleurodesis performed in our trust.This study was done in The Queen Elizabeth Hospital, Kings Lynn, United Kingdom.We looked at the medical pleurodesis performed from April 2008 to May 2010.The results were assessed against the British Thoracic Society guidelines for medical pleurodesis. We also looked at the side effects and success rate of the procedure.Forty three events were analysed in 41 patients.Fourteen patients were admitted in 2008, 18 patients in 2009 and 7 patients in 2010. Twenty seven (64%) were female. The indications for the procedure were malignant pleural effusion 83%, pneumothorax 9%, and effusion of unknown origin 7%. The procedure was done on the right side in 73% and 27% on the left side. Talc slurry was used as a sclerosing agent in 41 events and bleomycin in 2 patients. The amount of talc and dilutent varied among the procedures. Four gram talc was used in 25 events (70%) and eight gram in two events. The amount of dilutent used varied between 10 and 50 ml. Lignocaine was used only in 65% of patients whilst 32% received Oromorph for prevention of pain. The average post procedure survival was 2.24 months and 14 patients died within a month of the procedure. Therefore the accurate success rate is difficult to estimate. However, the measured success rate of the procedure was 39.5%. Three patients experienced complications pain, fever, or oxygen desturation.Medical pleurodesis is a simple,safe and effective procedure.We suggest that adherence with the guidelines is necessary to maintain the efficacy and consistency of the procedure.