TY - JOUR T1 - Where there's smoke there's fire! What is the function? JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p1118 AU - Peggy Radford Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p1118.abstract N2 - Morbidity and mortality from smoke inhalation occurs in victims of fire. This study's purpose is to report infant pulmonary function (IPL) in children exposed to smoke from a building fire. The children received care in another facility and were referred to our center for IPL. IPL was performed on 45 children; 23 females, 22 males mean age of 114 weeks; range 50 to 173 wks at the time of testing. Time to testing after the fire was 8.4 months (range 3-17mos). Conscious sedation was used for raised volume thoracoabdominal compression as the IPL technique. Pre-bronchodilator results were obtained on 45 children.View this table:Table 1Levalbuterol was given if the child remained sedated. 35 children had post bronchodilator IPL. There was no significant changed noted in FVC or FEV.5 however the change in FEF25-75(108.7% to 114.5%) was significant. IPL results were further divided into 2 groups based on Total Lung Capacity (TLC < 80%; TLC ≥ 80%).View this table:Table 2The low TLC group also had significantly lower FVC and FEV.5 than the normal TLC group. The results of 45 children showed low normal TLC and FVC. When the results compared abnormal TLC% versus normal TLC%, the low TLC% group also had significantly lower FVC and FEV.5 than normal TLC% group. These findings are similar to the decline in FVC found in World Trade Center workers. Longitudinal lung function data will be important to obtain to determine future recovery or decline in lung function and to collect future respiratory infection risks and complications. ER -