TY - JOUR T1 - Observation of pregnant women (PW) after severe pneumonia (P) with influenza A/H1N1 virus infection in 2009-2010: Long-term results JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p4359 AU - Tetyana Pertseva AU - Olga Cherkasova AU - Iryna Tyshchenko AU - Tetyana Kireyeva AU - Gennadiy Marinokha AU - Elina Tadzhiyeva Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p4359.abstract N2 - Aim: To analyze consequences of P in PW.Material, methods: Observation during 1 yr of 6 women who had severe viral-bacterial P associated with virus A/H1N1 in term of gestation (G) 21-33 wks. All pts were in need treatment in ICU due to ARDS. 1 woman had a live baby vaginally at G term 29 wks in ICU. Rehabilitation was performed. Blood tests (BT), spirometry, SaO2, lung CT were controlled.Results: At discharge from ICU: pts were dominated by moderate respiratory failure, restrictive type of PLT violation; mean SaO2 91.2±2.1%; CT: local lung tissue compactions, hypoventilation areas; BT: mild anemia, moderately elevated ESR. All pts' condition had improved during observation. BT was normalized for 1-2 months. After 1 yr 1 pt kept dyspnoea on severe exertion only; PLT indices had improved (Tabl.1), mean SaO2 97.6±1.4%. CT: 2 pts without pathology after 9 months, 4 pts had only compaction of interlobar pleura and pleural-costal, pleural-diaphragmatic adhesions after 1 yr. 5 pts gave birth vaginally at G term 36-39 wks. All babies are alive, without abnormalities in development.View this table:Table 1Conclusions: Severe P associated with virus A/H1N1 leads to structural and functional changes of respiratory system. Lung tissue compactions and reducing lung ventilation had undergone regression for 9-12 months. PW with P require prolonged observation and monitoring PLT, SaO2 and lung CT. ER -