PT  - JOURNAL ARTICLE
AU  - Winifried J. Randerath
AU  - D. Banerjee
AU  - M. Treml
AU  - W. Galetke
AU  - C. Priegnitz
AU  - A. Ali
AU  - S. Taheri
TI  - Efficacy of BiPAP AutoSV advanced in subjects with congestive heart failure and central apnea
DP  - 2011 Sep 01
TA  - European Respiratory Journal
PG  - p2231
VI  - 38
IP  - Suppl 55
4099  - http://erj.ersjournals.com/content/38/Suppl_55/p2231.short
4100  - http://erj.ersjournals.com/content/38/Suppl_55/p2231.full
SO  - Eur Respir J2011 Sep 01; 38
AB  - Introduction: Auto-Servo Ventilation effectively suppresses Sleep Disordered Breathing (SDB) in patients with Congestive Heart Failure (CHF). This study compared the efficacy of a new mode of ASV that incorporates an automatic EPAP (ASV-Advanced), with and without its Bi-Flex comfort feature, to manually titrated ASV (ASV) in patients with central SDB and CHF.Methods: Following diagnostic PSG and titration, patients underwent 3 consecutive treatment nights in a random order: ASV, ASV-Advanced and ASV-Advanced with Bi-Flex. For the ASV night, EPAP was set to the level determined during the titration night and IPAP set at EPAP+20cmH2O. For the ASV-Advanced nights, the device was set to automatically determine EPAP and IPAP pressures with a maximum pressure support of 20cmH2O. When activated, Bi-Flex was set to its maximum expiratory pressure relief. Data were analyzed with ANOVA and Bonferroni.Results: 10 males participated (mean ± SD: age 67.4±11.7 y, BMI 28.4±5.5 kg/m2, LVEF 25.7±5.7%). Sleep time and efficiency were similar.View this table:Table 1Conclusion: ASV-Advanced treats central SDB as effectively as ASV in patients with CHF.