TY - JOUR T1 - Systemic inflammation and nutritive status in patients with COPD JF - European Respiratory Journal JO - Eur Respir J VL - 38 IS - Suppl 55 SP - p3594 AU - Kateryna Gashynova Y1 - 2011/09/01 UR - http://erj.ersjournals.com/content/38/Suppl_55/p3594.abstract N2 - Nutritional abnormalities are frequently occurring systemic complication of COPD. They often determinate functional capacity, health status and mortality of patients (pts). However, causes and mechanisms of weight loss are still under investigation.Aim: The aim of study was to reveal influence of systemic inflammation on the nutritive status in pts with COPD.Study population and methods: 69 men with stable COPD (Stage II-III) were surveyed.Plasma C-reactive protein (CRP), spirometry, measurement of body mass index (BMI) and Fat Free Body Mass (FFBM) by means of bioelectrical impedance analysis were performed for all pts.Results: In accordance with CRP level all pts were divided on two groups: Group I – pts with CRP ≤ 2.87 mg/l; Group II – pts with CRP > 2.87 mg/l.Results of nutritive status examination present in table 1.View this table:Conclusion:Increasing of CRP leads to significant decreasing of FFBM in pts with COPD.Despite the fact, that mean BMI was within normal ranges in both groups, it was significantly lower in pts with high CRP.Systemic inflammation associates with increasing of the general weight loss rate. ER -