RT Journal Article
SR Electronic
T1 The influence of sensitisation to pollens and moulds on seasonal variations in asthma attacks
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 935
OP 945
DO 10.1183/09031936.00097412
VO 42
IS 4
A1 Cristina Canova
A1 Joachim Heinrich
A1 Josep Maria Anto
A1 Benedicte Leynaert
A1 Matthew Smith
A1 Nino Kuenzli
A1 Jan-Paul Zock
A1 Christer Janson
A1 Isa Cerveri
A1 Roberto de Marco
A1 Kjell Toren
A1 Thorarinn Gislason
A1 Dennis Nowak
A1 Isabelle Pin
A1 Matthias Wjst
A1 Jure Manfreda
A1 Cecilie Svanes
A1 Julian Crane
A1 Michael Abramson
A1 Michael Burr
A1 Peter Burney
A1 Deborah Jarvis
YR 2013
UL http://erj.ersjournals.com/content/42/4/935.abstract
AB No large study has described the seasonal variation in asthma attacks in population-based asthmatics in whom sensitisation to allergen has been measured.2637 young adults with asthma living in 15 countries reported the months in which they usually had attacks of asthma and had skin-prick tests performed. Differences in seasonal patterns by sensitisation status were assessed using generalised estimating equations.Most young adults with asthma reported periods of the year when their asthma attacks were more common (range: 47% in Sweden to 86% in Spain). Seasonal variation in asthma was not modified by sensitisation to house dust mite or cat allergens. Asthmatics sensitised to grass, birch and Alternaria allergens had different seasonal patterns to those not sensitised to each allergen, with some geographical variation. In southern Europe, those sensitised to grass allergens were more likely to report attacks occurred in spring or summer than in winter (OR March/April 2.60, 95% CI 1.70–3.97; OR May/June 4.43, 95% CI 2.34–8.39) and smaller later peaks were observed in northern Europe (OR May/June 1.25, 95% CI 0.60–2.64; OR July/August 1.66, 95% CI 0.89–3.10). Asthmatics reporting hay fever but who were not sensitised to grass showed no seasonal variations.Seasonal variations in asthma attacks in young adults are common and are different depending on sensitisation to outdoor, but not indoor, allergens.Seasonal variation in asthma attacks is associated with sensitisation to pollens and moulds, but not indoor allergens http://ow.ly/nsuRS