TY - JOUR T1 - Tuberculosis and airflow obstruction: evidence from the PLATINO study in Latin America JF - European Respiratory Journal JO - Eur Respir J SP - 1180 LP - 1185 DO - 10.1183/09031936.00083507 VL - 30 IS - 6 AU - A. M. B. Menezes AU - P. C. Hallal AU - R. Perez-Padilla AU - J. R. B. Jardim AU - A. Muiño AU - M. V. Lopez AU - G. Valdivia AU - M. Montes de Oca AU - C. Talamo AU - J. Pertuze AU - C. G. Victora A2 - , Y1 - 2007/12/01 UR - http://erj.ersjournals.com/content/30/6/1180.abstract N2 - The aim of the present study was to evaluate the association between history of tuberculosis and airflow obstruction. A population-based, multicentre study was carried out and included 5,571 subjects aged ≥40 yrs living in one of five Latin American metropolitan areas: Sao Paulo (Brazil); Montevideo (Uruguay); Mexico City (Mexico); Santiago (Chile); and Caracas (Venezuela). Subjects performed pre- and post-bronchodilator spirometry and were asked whether they had ever been diagnosed with tuberculosis by a physician. The overall prevalence of airflow obstruction (forced expiratory volume in one second/forced vital capacity post-bronchodilator <0.7) was 30.7% among those with a history of tuberculosis, compared with 13.9% among those without a history. Males with a medical history of tuberculosis were 4.1 times more likely to present airflow obstruction than those without such a diagnosis. This remained unchanged after adjustment for confounding by age, sex, schooling, ethnicity, smoking, exposure to dust and smoke, respiratory morbidity in childhood and current morbidity. Among females, the unadjusted and adjusted odds ratios were 2.3 and 1.7, respectively. In conclusion, history of tuberculosis is associated with airflow obstruction in Latin American middle-aged and older adults. ER -