RT Journal Article SR Electronic T1 The effect of OSAS on sick leave and work disability JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 1497 OP 1503 DO 10.1183/09031936.00044908 VO 32 IS 6 A1 B. Sivertsen A1 S. Øverland A1 N. Glozier A1 B. Bjorvatn A1 J. G. Mæland A1 A. Mykletun YR 2008 UL http://erj.ersjournals.com/content/32/6/1497.abstract AB The objective of the present study was to examine the independent contribution of symptoms of obstructive sleep apnoea syndrome (OSAS) to long-term sick leave and permanent work disability. Using a historical cohort design with 4 yrs of follow-up, information on sick leave and disability benefit recipiency were merged with health information from the Hordaland Health Study, carried out in western Norway during 1997–1999. Persons aged 40–45 yrs (n = 7,028) were assessed for self-reported symptoms of OSAS (snoring, breathing cessations and daytime sleepiness), body mass index, somatic conditions and other potential confounders. The outcomes, cumulative sick leave of ≥8 weeks and permanent work disability, were identified in records from the National Insurance Administration. After excluding participants with work disability at baseline, symptoms of OSAS were found to be a significant predictor of both subsequent long-term sick leave and permanent work disability. These effects remained significant after adjustment for a range of possible confounding factors. Daytime sleepiness showed the greatest explanatory power, followed by breathing cessations and snoring. It is concluded that self-reported symptoms of obstructive sleep apnoea syndrome are an independent risk factor for subsequent long-term sick leave and permanent work disability. These findings need to be replicated using objective measures of obstructive sleep apnoea syndrome.