PT  - JOURNAL ARTICLE
AU  - S Kivity
AU  - R Ganem
AU  - J Greif
AU  - M Topilsky
TI  - The combined effect of nifedipine and sodium cromoglycate on the airway response to inhaled hypertonic saline in patients with bronchial asthma
AID  - 10.1183/09031936.93.02060513
DP  - 1989 Jun 01
TA  - European Respiratory Journal
PG  - 513--516
VI  - 2
IP  - 6
4099  - http://erj.ersjournals.com/content/2/6/513.short
4100  - http://erj.ersjournals.com/content/2/6/513.full
SO  - Eur Respir J1989 Jun 01; 2
AB  - The combined effect of oral nifedipine and aerosolized sodium cromoglycate on the airway response to inhaled sodium chloride at increasing concentrations was randomly studied in 10 patients with bronchial asthma. Nifedipine (20 mg) protected the airways in 6 of the 10 patients, and sodium cromoglycate (20 mg) in all the 10 patients. Following both drugs, the airway response to hypertonic saline was further reduced when compared to each drug on its own. It is concluded that the combination of nifedipine with sodium cromoglycate might be of benefit in the treatment of difficult asthmatic patients.