RT Journal Article
SR Electronic
T1 Interstitial lung diseases in collagen vascular diseases
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 69S
OP 80S
DO 10.1183/09031936.01.18s320069
VO 18
IS 32 suppl
A1 C. Lamblin
A1 C. Bergoin
A1 T. Saelens
A1 B. Wallaert
YR 2001
UL http://erj.ersjournals.com/content/18/32_suppl/69S.abstract
AB In this review, a clinical update is presented of the most important collagen vascular diseases (CVDs) and the different types of interstitial lung disease (ILD) encountered in these CVDs. These CVDs represent a heterogenous group of immunologically mediated inflammatory disorders with a large variety of affected organs besides the lungs.The frequency, clinical presentation, prognosis and response to therapy vary depending on the histological pattern (usual interstitial pneumonia, desquamative interstitial pneumonia, organising pneumonia, diffuse alveolar damage, nodular lesions, etc.), as well as on the underlying CVD (scleroderma, rheumatoid arthritis, systemic lupus erythematosus, dermatopolymyositis, Sjögren's syndrome or mixed connective tissue disease).The diagnosis of most of these CVDs is based on a number of criteria; in several of these, however, lung involvement is not part of the diagnostic criteria. In addition, there may be overlaps between several of these CVDs.Optimal treatment varies depending on the type of collagen vascular disease and the presence of interstitial lung disease, although in many cases, a combination of corticosteroids and cytostatic drugs are given.