%0 Journal Article %A Elise Dupuis-Lozeron %A Grégoire Gex %A Patrick Pasquina %A Pierre-Olivier Bridevaux %A Jean-Christian Borel %A Paola Gasche-Soccal %A Wolfram Windisch %A Jean-Louis Pépin %A Jean-Paul Janssens %A Dan Adler %T Development and validation of a simple tool for the assessment of home NIV: the S3-NIV questionnaire %D 2018 %R 10.1183/13993003.011822018 %J European Respiratory Journal %P 1801182 %X Patient-centered outcomes are significantly modified by long-term home non-invasive ventilation (NIV), but a short, self-administered, specific tool for routine clinical assessment is lacking. The aim of this study was to develop and validate the S3-NIV questionnaire, a short questionnaire to measure respiratory symptoms, sleep quality and NIV-related side-effects.Stable patients under long-term home NIV were recruited from three outpatient NIV services. Questionnaire development consisted of a selection of core items for analysis, followed by item reduction, validation and test-retest reliability.338 patients completed a 22-item questionnaire. Eleven items were removed because of non-scalability (n=2), redundancy (n=8) and lack of fit (n=1). The final version of the S3-NIV questionnaire consisted of 11 items covering two dimensions: “respiratory symptoms” (Cronbach alpha=0.84) and “sleep & NIV-related side-effects” (Cronbach alpha=0.77). Convergent validity was high between the “respiratory symptoms” subscale of the S3-NIV questionnaire and the St. George's Respiratory Questionnaire (rho=−0.76; p<0.001), as well as the “sleep & NIV side-effects” subscale and the Quebec Sleep Questionnaire (rho=0.51; p<0.001). The S3-NIV questionnaire had a good test-retest reliability after 4 weeks (intraclass correlation coefficient=0.72).The S3-NIV questionnaire is a short, valid and repeatable, self-completed tool for the routine clinical assessment of patients undergoing home NIV.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Elise Dupuis-LozeronGrégoire GexPatrick PasquinaOlivier BridevauxChristian BorelPaola Gasche-SoccalWolfram WindischConflict of interest: Dr. Pépin has nothing to disclose.Paul JanBensConflict of interest: Dr. Adler has nothing to disclose. %U https://erj.ersjournals.com/content/erj/early/2018/09/20/13993003.011822018.full.pdf