TY - JOUR T1 - Should reversibility be assessed in all asthmatic children with normal spirometry? JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00373-2018 VL - 52 IS - 2 SP - 1800373 AU - Edouard Dufetelle AU - Plamen Bokov AU - Christophe Delclaux AU - Nicole Beydon Y1 - 2018/08/01 UR - http://erj.ersjournals.com/content/52/2/1800373.abstract N2 - Spirometry is usually normal at baseline in asthmatic children referred for pulmonary function tests (PFTs) [1]; however, a positive response to bronchodilator can be evidenced in these children [2, 3]. The detection of a significant bronchodilator response (BDR) is not meaningless as it confirms asthma and independently predicts subsequent level of forced expiratory volume in 1 s (FEV1) [4], response to inhaled corticosteroids [5] or correlates to increased exhaled NO [6].In asthmatic children with normal baseline spirometry, a significant reversibility is detected in only 4.9% of cases http://ow.ly/RrBK30k9WIs ER -