TY - JOUR T1 - Should reversibility be assessed in all asthmatic children with normal spirometry? JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00373-2018 SP - 1800373 AU - Edouard Dufetelle AU - Plamen Bokov AU - Christophe Delclaux AU - Nicole Beydon Y1 - 2018/01/01 UR - http://erj.ersjournals.com/content/early/2018/05/24/13993003.00373-2018.abstract N2 - Spirometry is usually normal at baseline in asthmatic children referred for pulmonary function testing (PFTing) [1], still a positive response to bronchodilator can be evidenced in these children [2, 3]. The detection of a significant bronchodilator response (BDR) is not meaningless as it confirms asthma, and independently predicts subsequent level of forced expiratory volume in 1 s (FEV1) [4], response to inhaled corticosteroids [5], or correlates to increased exhaled NO [6].In asthmatic children with normal baseline spirometry, a significant reversibility is detected in only 4.9% of casesFootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Dufetelle has nothing to disclose.Conflict of interest: Dr. Bokov has nothing to disclose.Conflict of interest: Dr. Delclaux has nothing to disclose.Conflict of interest: Dr. Beydon has nothing to disclose. ER -