RT Journal Article
SR Electronic
T1 Social deprivation and prognosis in Scottish patients with pulmonary arterial hypertension
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1700444
DO 10.1183/13993003.00444-2017
VO 51
IS 2
A1 Katherine Pellino
A1 Simon Kerridge
A1 Colin Church
A1 Andrew J. Peacock
A1 Timothy Crowe
A1 Geeshath Jayasekera
A1 Martin K. Johnson
A1 Alison M. MacKenzie
YR 2018
UL http://erj.ersjournals.com/content/51/2/1700444.abstract
AB Several demographic and clinical factors have prognostic significance in idiopathic pulmonary arterial hypertension (IPAH). Studies in China and the USA have suggested an association between low socioeconomic status and reduced survival. The impact of social deprivation on IPAH survival in the UK is not known.280 patients with IPAH and hereditary PAH (HPAH) attending the Scottish Pulmonary Vascular Unit (Glasgow, UK) were assigned to social deprivation quintiles using the Scottish Index of Multiple Deprivation database. The association between survival and social deprivation quintile was assessed using Cox proportional hazards regression analysis.The distribution of IPAH/HPAH patients was more socially deprived than would be expected based on Scottish citizenry as a whole (Chi-squared 16.16, p=0.003), suggesting referral and access to care is not impeded by socioeconomic status. Univariate analysis demonstrated no significant association between social deprivation and survival (p=0.81), and this association failed to reach significance with inclusion of time, sex and age as covariates in the model (p=0.23). There were no statistically significant correlations between social deprivation and baseline clinical variables of prognostic importance except for age, sex and quality of life.Social deprivation is not a significant referral barrier or prognostic factor for IPAH and HPAH in Scotland.Social deprivation is not a significant referral barrier or prognostic factor for IPAH and HPAH in Scotland http://ow.ly/N7aL30gE4ui