TY - JOUR T1 - Diagnosis on community-acquired pneumonia (CAP) in patients with congestive heart failure (CHF) JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/1393003.congress-2017.PA4521 VL - 50 IS - suppl 61 SP - PA4521 AU - Andrey Bobylev AU - Svetlana Rachina AU - Sergey Avdeev AU - Vladimir Mladov Y1 - 2017/09/01 UR - http://erj.ersjournals.com/content/50/suppl_61/PA4521.abstract N2 - Background: Diagnosis of CAP presents difficulties in patients with concomitant CHF.Aim: To assess value of routine clinical practice methods/tests and serum biomarkers for diagnosis of CAP in patients with CHF.Methods: Prospective observational study included adult patients presented at emergency unit with suspected CAP and concomitant CHF. In addition to routine tests/procedures C-reactive protein (CRP), procalcitonin (PCT), interleukin-6 (IL-6), tumor necrosis factor α (TNFα), brain natriuretic peptide (BNP) levels were measured. Chest computed tomography was done to verify/exclude CAP. Standard stalistical tools were applied; p value <0.05 was considered significant.Results: Altogether 70 suitable patients were enrolled. Characteristics of patients with verified CAP (group 1) and CHF decompensation (group 2) are presented in table 1.View this table:Table 1. Copmarison of patients with CAP and CHF decompensation*normal ranges: CRP 0-8; PCT <0.1; IL-6 0-10; TNFα 0-6; BNP 0-100Conclusion: Clinical presentation, routine lab tests and chest X-ray findings seem to have limited value in diagnosis of CAP among patients with concomitant CHF. CRP, PCT, IL-6 can be useful for differentiating CAP from CHF worsening. ER -