TY - JOUR T1 - European Respiratory Society guidelines for the management of adult bronchiectasis JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00629-2017 VL - 50 IS - 3 SP - 1700629 AU - Eva Polverino AU - Pieter C. Goeminne AU - Melissa J. McDonnell AU - Stefano Aliberti AU - Sara E. Marshall AU - Michael R. Loebinger AU - Marlene Murris AU - Rafael Cantón AU - Antoni Torres AU - Katerina Dimakou AU - Anthony De Soyza AU - Adam T. Hill AU - Charles S. Haworth AU - Montserrat Vendrell AU - Felix C. Ringshausen AU - Dragan Subotic AU - Robert Wilson AU - Jordi Vilaró AU - Bjorn Stallberg AU - Tobias Welte AU - Gernot Rohde AU - Francesco Blasi AU - Stuart Elborn AU - Marta Almagro AU - Alan Timothy AU - Thomas Ruddy AU - Thomy Tonia AU - David Rigau AU - James D. Chalmers Y1 - 2017/09/01 UR - http://erj.ersjournals.com/content/50/3/1700629.abstract N2 - Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent exacerbations in many patients. There have been no previous international guidelines.The European Respiratory Society guidelines for the management of adult bronchiectasis describe the appropriate investigation and treatment strategies determined by a systematic review of the literature.A multidisciplinary group representing respiratory medicine, microbiology, physiotherapy, thoracic surgery, primary care, methodology and patients considered the most relevant clinical questions (for both clinicians and patients) related to management of bronchiectasis. Nine key clinical questions were generated and a systematic review was conducted to identify published systematic reviews, randomised clinical trials and observational studies that answered these questions. We used the GRADE approach to define the quality of the evidence and the level of recommendations. The resulting guideline addresses the investigation of underlying causes of bronchiectasis, treatment of exacerbations, pathogen eradication, long term antibiotic treatment, anti-inflammatories, mucoactive drugs, bronchodilators, surgical treatment and respiratory physiotherapy.These recommendations can be used to benchmark quality of care for people with bronchiectasis across Europe and to improve outcomes.The publication of the first ERS guidelines for bronchiectasis http://ow.ly/wQSO30dU0nE ER -