TY - JOUR T1 - Addressing unmet needs in understanding asthma mechanisms JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02448-2016 VL - 49 IS - 5 SP - 1602448 AU - Michael R. Edwards AU - Sejal Saglani AU - Jurgen Schwarze AU - Chrysanthi Skevaki AU - Jaclyn A. Smith AU - Ben Ainsworth AU - Mark Almond AU - Evangelos Andreakos AU - Maria G. Belvisi AU - Kian Fan Chung AU - William Cookson AU - Paul Cullinan AU - Catherine Hawrylowicz AU - Marek Lommatzsch AU - David Jackson AU - Rene Lutter AU - Benjamin Marsland AU - Miriam Moffatt AU - Mike Thomas AU - J. Christian Virchow AU - Georgina Xanthou AU - Jessica Edwards AU - Samantha Walker AU - Sebastian L. Johnston Y1 - 2017/05/01 UR - http://erj.ersjournals.com/content/49/5/1602448.abstract N2 - Asthma is a heterogeneous, complex disease with clinical phenotypes that incorporate persistent symptoms and acute exacerbations. It affects many millions of Europeans throughout their education and working lives and puts a heavy cost on European productivity. There is a wide spectrum of disease severity and control. Therapeutic advances have been slow despite greater understanding of basic mechanisms and the lack of satisfactory preventative and disease modifying management for asthma constitutes a significant unmet clinical need. Preventing, treating and ultimately curing asthma requires co-ordinated research and innovation across Europe. The European Asthma Research and Innovation Partnership (EARIP) is an FP7-funded programme which has taken a co-ordinated and integrated approach to analysing the future of asthma research and development. This report aims to identify the mechanistic areas in which investment is required to bring about significant improvements in asthma outcomes.The European Asthma Research and Innovation Partnership (EARIP) prioritises unmet needs in asthma mechanisms research http://ow.ly/zroI30a9MUs ER -