RT Journal Article SR Electronic T1 2017 ERS/ATS standards for single-breath carbon monoxide uptake in the lung JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 1600016 DO 10.1183/13993003.00016-2016 VO 49 IS 1 A1 Brian L. Graham A1 Vito Brusasco A1 Felip Burgos A1 Brendan G. Cooper A1 Robert Jensen A1 Adrian Kendrick A1 Neil R. MacIntyre A1 Bruce R. Thompson A1 Jack Wanger YR 2017 UL http://erj.ersjournals.com/content/49/1/1600016.abstract AB This document provides an update to the European Respiratory Society (ERS)/American Thoracic Society (ATS) technical standards for single-breath carbon monoxide uptake in the lung that was last updated in 2005. Although both DLCO (diffusing capacity) and TLCO (transfer factor) are valid terms to describe the uptake of carbon monoxide in the lung, the term DLCO is used in this document. A joint taskforce appointed by the ERS and ATS reviewed the recent literature on the measurement of DLCO and surveyed the current technical capabilities of instrumentation being manufactured around the world. The recommendations in this document represent the consensus of the taskforce members in regard to the evidence available for various aspects of DLCO measurement. Furthermore, it reflects the expert opinion of the taskforce members on areas in which peer-reviewed evidence was either not available or was incomplete. The major changes in these technical standards relate to DLCO measurement with systems using rapidly responding gas analysers for carbon monoxide and the tracer gas, which are now the most common type of DLCO instrumentation being manufactured. Technical improvements and the increased capability afforded by these new systems permit enhanced measurement of DLCO and the opportunity to include other optional measures of lung function.Updated technical standards for measuring DLCO (TLCO) including the use of rapid gas analyser systems http://ow.ly/QUhv304PMsy