PT - JOURNAL ARTICLE AU - Bharat Gopal TI - Role of EBUS-guided TBNA in CT reported isolated tubercular mediastinal lymphadenopathy AID - 10.1183/13993003.congress-2016.PA2110 DP - 2016 Sep 01 TA - European Respiratory Journal PG - PA2110 VI - 48 IP - suppl 60 4099 - http://erj.ersjournals.com/content/48/suppl_60/PA2110.short 4100 - http://erj.ersjournals.com/content/48/suppl_60/PA2110.full SO - Eur Respir J2016 Sep 01; 48 AB - Introduction: EBUS has an established role for the diagnosis of mediastinal lymphadenopathy secondary to malignancy and sarcoidosis limited data describing the utility of this technique in the diagnosis of tuberculous mediastinal lymphadenitis.Aim: Isolated Tubercular Mediastinal Lymphadenopathy (ITML) is an often encountered problem.More often than not treatment is started on the basis of CT findings.We decided to check the senstivity & specificity of CT reported ITML with EBUSResults: Between January 2014 and Dec 2014,100 patients with CT reported IMTL were subjected to EBUS guided TBNA and samples were referred for mycobacteriological analysis.The results from these procedures were reviewed for Cytology,Mycobacteriology,TB cultures,Histolopathology & Gene Xpert for TB.Cytology results 84-Granulomatous Lymphadenitis with Necrotising 54 and non necrotising 30.The Smear for AFB-Positive in 4 .The Cytology or Histology (Core Tissue) sent in 32 patients showed necrotising granulomatous inflammation in 18 and non necrotising granulomatous inflammation in 10.TB Cultures Positive in 20 with 1 case showed XDR .Gene Xpert Positive in 12 out of 44 samples sent with No Rifampicin Resistance.True Positives were defined as 1) Culture positive and/or Gene Xpert Positive 2)Strong Clinical Suspicion and/or AFB positive and pathology s/o Necrotising granulomas By this criteria 58 / 100 ( 58 %) were confirmed with Tuberculosis.Conclusions: EBUS is a useful technique for confirmation of IMTL. The Sensitivity of CT reported IMTL for microbiologically confirmed TB estimated at 58 % .Utility of Gene Xpert still debatable as a diagnostic tool in Extrapulmonary TB.