RT Journal Article SR Electronic T1 Malignant pleural effusion and incidence of pleural thickening in thorax CT JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA5083 DO 10.1183/13993003.congress-2016.PA5083 VO 48 IS suppl 60 A1 Ana Jaureguizar Oriol A1 Esteban Perez Rodriguez A1 Paola Arrieta Narváez A1 Rosa Mirambeaux Villalona A1 Patricia Castro Acosta A1 Beatriz Martin Garcia A1 Esther Barbero Herranz YR 2016 UL http://erj.ersjournals.com/content/48/suppl_60/PA5083.abstract AB Introduction:Pleural thickening and nodulation (pathological)in pleural effusions, suggest malignancy etiology.Objectives: To analyse the incidence of pathological pleural by thorax CT in malignant pleural effusions(MPE). To assess the tumoral parameters related to pleural thickening or nodular.Material and method: From 1994-2015,3316 pleural effusions are included in our date base by a protocol(pH, biochemical,ADA,count cell,cytology and biopsy). The last 100 MPE confirmed by cytology or closed pleural biopsy have been studied. In all cases the CT were valued the thickening (>10mm parietal,>7 mm diaphragmatic)or nodular images. Descriptive statistical analysis was realized.Results: From the 100 cases of MPE,58 were men (average age 68.5+-13 years).The volume of MPE was 47+-28.1%. 73 of 91(80%) showed pathological pleural CT:28 nodules,7 diaphragmatic thickening and 38 thickening in other pleural location. Cytology was malignant in 63 of 73(86%)in pathological pleura. Pleural biopsy was realized in 23 cases:15 of 20(75%)with pleural thickening were positive for malignancy(Carcinomas, mesothelioma,lymphoma). Depending on tumour origin, thickening was found from lung cancer in 35 of 46(76%), and from metastases in other locations in 83%.Conclusions: MPE presents pleural thickening in 80% of the cases.Diagnosis of MPE by cytology and biopsy show similar efficiency.Metastases of malignant pleural effusions, show pleural thickening frequently.