@article {ShottonPA1874, author = {Kieran Shotton and Henry Walker and Christopher Johns and Dave Capener and Charlie Elliot and Robin Condliffe and Thanos Charalampopoulos and David Kiely and Jim Wild and Andrew Swift}, title = {Right ventricular MRI characteristics in patients with borderline pulmonary hypertension}, volume = {48}, number = {suppl 60}, elocation-id = {PA1874}, year = {2016}, doi = {10.1183/13993003.congress-2016.PA1874}, publisher = {European Respiratory Society}, abstract = {Pulmonary hypertension (PH) is defined as a mean pulmonary artery pressure (mPAP) >= 25mmHg at right heart catheterization. An mPAP of 21-24mmHg is termed borderline PH. This study investigates cardiac magnetic resonance (CMR) imaging characteristics of patients with borderline PH.Consecutive patients who underwent CMR at 1.5T at a PH centre between April 2012 and January 2016 were identified. Exclusion criteria were non-diagnostic imaging or RHC \>48 hours from CMR. All variables were compared between patients with normal mPAP (<= 20mmHg) and a borderline group (21-24 mmHg) using an independent samples t-test and bilogistic regression.Of 1800 consecutive patients with suspected PH, 128 patients met the inclusion criteria. In the full cohort, large RVEDVI (p\<0.001), RVESVI (p\<0.001), Interventricular septal (IVS) angle (p=0.003) and LA volume (p=0.014) were significantly higher in the borderline group. At bilogistic regression, borderline PH was independently associated with IVS angle and RVEDVI.Subgroup analysis of patients with connective tissue disease (N=49) revealed raised systolic IVS angle (p=0.048) in borderline patients (N=22). In patients with lung disease (N=60), borderline patients (N=32) had raised RVEDVI (p=0.001), RV mass index (p=0.028) and IVS angle (p=0.05). LHD patients (N=16) with borderline pressures (N=9) had raised RVEDVI (p=0.022) and RV mass index (p=0.041). Patients with thromboembolic disease (N=36) with borderline pressures (N=18) had raised RV mass index (p=0.026).Patients with borderline PH have evidence of RV remodelling but preserved RV functional metrics when compared to patients with normal PA pressure.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/48/suppl_60/PA1874}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }