RT Journal Article SR Electronic T1 Respiratory muscles trainings are effective in lowering the pneumonia frequency in patients with heart failure and chronic obstructive pulmonary disease JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3773 DO 10.1183/13993003.congress-2016.PA3773 VO 48 IS suppl 60 A1 Elena Kolesnikova A1 Gregory Arutyunov A1 Olga Kostyukevich A1 Anna Rylova YR 2016 UL http://erj.ersjournals.com/content/48/suppl_60/PA3773.abstract AB Purpose: To study the effect of long-term respiratory muscles trainings (RMT) in patients with HF and chronic obstructive pulmonary disease (COPD) on the frequency of pneumonia and heart faailure progression.Methods: 73 patients 63,5±3,7 yrs old with NYHA III-IV HF and COPD were randomized to either an exercise training group (EG)(37pts) or to a control group. The CG patients had standard CR according to the national guidelines. The EG participated additionally in a RMT with gradual increase of inspire and expire resistance. Trainings were held for 20-30 min 1-2 times every day for 12 months. VO2 peak, maximal inspiratory mouth pressure (PImax) and the frequency of hospitalizations and lethal events were evaluated at baseline and every 12 weeks during 1 year.Results: RMT as a part of comprehensive rehabilitation increased physical capacity (VOat baseline 9.06 ±2,35 ml/kg/min in EG vs 9.11±4,04 ml/kg/min in CG, p>0,05; 12,87±2,75 ml/kg/min in EG vs 7,69±2,16 ml/kg/min in CG, p<0,05, in 12 months), enhanced ventilation (VC at baseline 56.7± 3.9% in TG vs 57.01±4.5% in CG; 59.4±1.2% vs 51,9 ±2.8% p<0,05, in 12 months; FVC 44.8±3.1% vs 45.1±1.4% at baseline; 48.2±2.4% in TG vs 43.1±2.1% in CG, p<0,05, in 12 months). 12% of TG patients had pneumonia during 1 year vs 19% of patients in CG. In CG pneumonia provoked HF progression, in TG there was no statistically significant correlation between pneumonia and HF.Conclusion: RMT in patients with NYHA class III-IV HF and COPD increase physical capacity, enhanced ventilation and reduce frequency of pneumonia and related HF progression.