TY - JOUR T1 - Weight-based oxygen flow rate is predictive of successful weaning of long-term oxygen therapy in babies with bronchopulmonary dysplasia JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.PA1298 VL - 48 IS - suppl 60 SP - PA1298 AU - Katherine Millard AU - Matthew Hurley AU - Andrew Prayle AU - Sarah Spencer AU - Dushyant Batra AU - Jayesh M. Bhatt Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/PA1298.abstract N2 - Background: There are currently no evidence-based guidelines to wean home oxygen in babies with bronchopulmonary dysplasia(BPD). We perform serial overnight oximetry guiding a wean to a reduced flow rate until discontinuation if babies meet set targets(wean by decrements of 0.1L/min until a flow rate of 0.1L/min is achieved→ 2 hour day time oximetry in air→ increasing awake time off oxygen over 2 weeks→ overnight air study→ discontinue). Previous small studies suggest that flow rates of ≤20 ml/kg/min are predictive of successful oxygen discontinuation.Aims: To evaluate the pre-weaning weight-based flow rates of babies successfully weaned from oxygen.Methods: 173 babies were successfully weaned from home oxygen for BPD. The weight of the child at time of oxygen discontinuation was recorded. Babies without a recorded weight were excluded (n=24). Flow rates for each baby immediately prior to coming off oxygen were calculated in ml/kg/min.Results: This analysis includes 5 babies who were successfully weaned from a flow rate of ≤20 ml/kg/min i.e. weaned from an absolute flow rate of ≥0.1 L/min, or who had day and night air studies carried out on the same day, thereby reducing the duration of home oxygen therapy. Number of babies149Mean weight in Kg(SD) at cessation of oxygen6.55(± 1.75)Flow rate in ml/kg/min(SD)16.52(± 4.79)Number of babies successfully weaned at flow rates ≤20 ml/kg/min121/149(81.2%)Conclusions:Successful weaning from home oxygen in a large cohort of babies with BPD is associated with pre-weaning flow rates of ≤20 ml/kg/min. This validates previous suggestions that this may be a useful predictor of readiness to come off oxygen. ER -