TY - JOUR T1 - Ultrasonic assessment of accessory respiratory muscles (RM) in young men and women with joint hypermobility JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.PA3795 VL - 48 IS - suppl 60 SP - PA3795 AU - Lemeschewskij Alexandr AU - Lemiasheuskaya Sviatlana AU - Alekseev Sergey AU - Makarevich Alexandr Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/PA3795.abstract N2 - Introduction: Connective tissue laxity identifies in various sites throughout the body. Aim was to estimate the accessory RM using ultrasound scanner.Methods: We examined 34 young men (median age 19 yrs; BMI 22,3 kg/m2, smokers 41%, packs/yrs 0,75) and 41 young women (median age 20 yrs; BMI 20,2 kg/m2, smokers 7%, packs/yrs 0,13). The peak histograms of active expiration muscles (external and internal oblique abdominal (extOAM and intOAM), transverses and rectus abdominal and internal intercostals) and accessory muscles of inspiration were detected by ultrasonic scanner. We studied indices reflecting muscle tissue echogenicity: homogeneity (H), structural density (SD) and echogenicity (E). The Beighton (B) score was used for showing up hypermobility (the 1st group (n=20 men) B score 1-3, the 2nd group (n=14 men) B score 4-9, the 3rd group (n=17 women) B score 1-3, the 4th group (n=24 men) B score 4-9).Results: We identified significantly decreasing echogenicity of muscles (fall of the index E and growth of the indices H, SD) only in the 2nd group of extOAM, intOAM, transverses abdominal and external intercostals in comparison with the 1st group. The index E of extOAM was similar in the 3rd group and in the 4th group: 3,3 (2,9;4,4) and 3,2 (2,7; 4,3) respectively. The index H was 23 (21;27) in the 3rd group and in the 4th group of extOAM 24(20;29). So was SD 1661 (1280;1914) and 1408 (1159; 1929) respectively.Conclusions: Probably ascertained changes of accessory RM in young menwith hypermobility (B score 4-9) come out of hypotrophy muscle tissue. We did not find significant changes in the muscle tissue of young women with increasing joint hypermobility. ER -