PT - JOURNAL ARTICLE AU - Hanne Sorger AU - Tore Amundsen AU - Erlend Fagertun Hofstad AU - Thomas Langø AU - Håkon Olav Leira TI - A multimodal image guiding system for navigated endobronchial ultrasound (EBUS): Human pilot AID - 10.1183/13993003.congress-2016.PA2038 DP - 2016 Sep 01 TA - European Respiratory Journal PG - PA2038 VI - 48 IP - suppl 60 4099 - http://erj.ersjournals.com/content/48/suppl_60/PA2038.short 4100 - http://erj.ersjournals.com/content/48/suppl_60/PA2038.full SO - Eur Respir J2016 Sep 01; 48 AB - Introduction: Intraoperative navigation in endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) might improve position control and facilitate precise sampling.Aims and objectives: We wanted to test the clinical usefulness of a new multimodal image guiding system with navigated EBUS for mediastinal lymph node TBNA.Methods: Five patients with lung tumor referred for EBUS-TBNA consented to study participation. Preoperative computed tomography (CT) images were preprocessed in an in-house platform for electromagnetic (EM) navigated EBUS, including definition of target lymph nodes. Automatic CT-to-patient registration was performed in the first phase of EBUS. The position of the distal EBUS-scope was displayed together with corresponding 2D CT slices, airway and lymph node models from CT, and real-time 2D ultrasound (US) images for localizing, visualizing and sampling target lymph nodes.Results: The EM navigated EBUS system presented high-quality fused CT and US images, facilitated fast, precise and successful target localization and sampling, and provided a comprehensive overview visualization of the current position of the EBUS-scope. Conclusions: The multimodal image guided EBUS system was feasible for precise lymph node visualization and sampling in five patient cases. The system is currently subject to an extended human study.