TY - JOUR T1 - Clinical characteristics of seasonal rhinitis and co-existence with asthma JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.PA4200 VL - 48 IS - suppl 60 SP - PA4200 AU - Ebru Özdemir AU - Esra Karabiber AU - Özge Öztürk Aktas AU - Ebru Çelebioglu AU - Gül Karakaya AU - A. Fuat Kalyoncu Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/PA4200.abstract N2 - Background: The impact of the upper on the lower airways and the co-existence of asthma and rhinitis is documented in numerous epidemiological studies. Seasonal allergic rhinitis (SAR) is usually considered to be a pure IgE-mediated disease induced by seasonal aeroallergens especially pollens however the inflammation is not restricted to nasal mucosa; it also affects other neighboring mucosal surfaces.Aim: The aim was to determine the clinical charateristics of patients with SAR and risk factors for asthma.Methods: A total of 222 patients with diagnosis of SAR were enrolled in our adult outpatient allergy clinic in Hacettepe University, between September 2014- July 2015. Data about demographic features, cigarette smoking, accompanying atopic diseases, skin prick test (SPT) results, history of familial atopic diseases were collected.Results: Of 222 patients, 137 were female (61.7%) and the mean age was 32.24±9.99 years. The mean age of onset of the SAR was 23.11±11.01 years. The most common referral complaints of the patients were nasal symptoms in 87.4%. The most common accompanying atopic disease was asthma in 36%, followed by food allergy in 16%. SPT were positive for pollen in 134 patients (64.4%) and the most common sensitivity was against Phleum pratense (63.1%). Familial atopy, type of referral complaints, food allergy, metal allergy, immunotherapy history, over weight (BMI>25) and mode of delivery were found to be associated with the development of asthma in patients with SAR.Discussion: The co-existence of SAR and asthma in our study was 36%. The patients with SAR who are at high risk for developing asthma should be investigated and suggested recommendations for preventable risk factors. ER -