PT - JOURNAL ARTICLE AU - Maia P. Smith AU - Andrea von Berg AU - Dietrich Berdel AU - Carl-Peter Bauer AU - Barbara Hoffmann AU - Sibylle Koletzko AU - Dennis Nowak AU - Joachim Heinrich AU - Holger Schulz TI - Physical activity is not associated with spirometric indices in lung-healthy German youth AID - 10.1183/13993003.01408-2015 DP - 2016 Aug 01 TA - European Respiratory Journal PG - 428--440 VI - 48 IP - 2 4099 - http://erj.ersjournals.com/content/48/2/428.short 4100 - http://erj.ersjournals.com/content/48/2/428.full SO - Eur Respir J2016 Aug 01; 48 AB - In lung disease, physical activity improves lung function and reduces morbidity. However, healthy populations are not well studied. We estimate the relationship between spirometric indices and accelerometric physical activity in lung-healthy adolescents.895 nonsmoking German adolescents without chronic lung disease (45% male, mean±sd age 15.2±0.26 years) from the GINIplus and LISAplus cohorts completed questionnaires, spirometry, 7-day accelerometry and an activity diary. Physical activity was measured as minutes, quintiles and regularity of daily moderate, vigorous and moderate-to-vigorous physical activity (MVPA), participation in sport and active commuting to school. Primary outcomes were forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), FEV1/FVC and forced expiratory flow at 25–75% of FVC; they were separately correlated with physical activity and adjusted for confounders of respiratory function, including early-life exposures.Adolescents averaged 40 min MVPA per day, typical for European youth. 79% participated in sports and 51% commuted actively. An association was suggested between 3% higher FVC (∼100 mL) and either extreme MVPA quintile or percentage of days with >30 min MVPA (p<0.05). However, after Bonferroni correction all associations between spirometry, active lifestyle and physical activity were nonsignificant.Spirometric indices were not significantly associated with active lifestyle or measures of activity in lung-healthy adolescents after adjustment for confounding and multiple-comparison artefacts.In lung-healthy adolescents, spirometric indices were not associated with measures of physical activity http://ow.ly/YN4Nt