TY - JOUR T1 - Deficient interleukin-17 production in response to <em>Mycobacterium abscessus</em> in cystic fibrosis JF - European Respiratory Journal JO - Eur Respir J SP - 990 LP - 993 DO - 10.1183/13993003.00446-2015 VL - 47 IS - 3 AU - Katharina L. Becker AU - Jakko van Ingen AU - Jaap ten Oever AU - Peter J. Merkus AU - Gerben Ferwerda AU - Mihai G. Netea AU - Cecile Magis-Escurra AU - Monique H. Reijers AU - Frank L. van de Veerdonk Y1 - 2016/03/01 UR - http://erj.ersjournals.com/content/47/3/990.abstract N2 - The respiratory tract of patients with cystic fibrosis (CF) is colonised with a high diversity of micro-organisms. Nontuberculous mycobacteria (NTM) show a high and increasing prevalence. 40% of these positive NTM cultures are caused by Mycobacterium abscessus [1], one of the rapidly growing NTMs present in the environment. Patients with M. abscessus infection are difficult to treat, due to natural and acquired antibiotic resistance [2, 3], and an infection with M. abscessus is controversially discussed as a contraindication for lung transplantation [4].Mycobacterium abscessus-specific IL-17 deficiency is present in cystic fibrosis patients with M. abscessus http://ow.ly/U2DNLThe authors thank Liesbeth Jacobs and Trees Jansen (Dept of Internal Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands) for their help with the cytokine stimulation assay. ER -