TY - JOUR T1 - Environmental factors in schools determining exercise-induced symptoms in children JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2015.PA2555 VL - 46 IS - suppl 59 SP - PA2555 AU - Iwona Stelmach AU - Lukasz Cichalewski AU - Wlodzimierz Stelmach AU - Daniela Podlecka AU - Joanna Jerzynska Y1 - 2015/09/01 UR - http://erj.ersjournals.com/content/46/suppl_59/PA2555.abstract N2 - Background: The results of our previous study focused on the high prevalence of exercise related bronchoconstriction (EIB) during physical education lesson in a general population of schoolchildren.Objectives: To determine the potential environmental factors (such as humidity, temperature, air pressure, allergen exposure) in schools that could be predictive for the presence of exercise-induced symptoms in children during physical education.Methods: 480 schoolchildren from 5 public schools were enrolled. All children attended 45 minute PE lesson with similar exercise intensity. Pulmonary function tests were performed before and immediately after PE lesson. The diagnosis of EIB was defined as a FEV1 decrease from baseline of ≥ 10% with exercise. All dust samples were prepared for measurements and performed by Indoor Biotechnologies Laboratory (Cardiff, UK) and analyzed using a multiplex assay kit (MARIA). The following allergens were measured: dust mite, cat, mouse, cockroach, mold.Results: 461 participants were included into the analysis. After PE lesson, 16,3% children suffered from cough, 0,9% reported dyspnea and 11,1% had more than 10% fall in FEV1 from baseline. Among all participants, 6,9% had doctors' diagnosed asthma. EIB was not affected by age, gender, BMI, asthma diagnosis. Only cough (OR: 2.11, 95%CI: 1.06-4.03; p=0.0141) was independently associated with EIB. Atmospheric conditions didn't significantly differe between schools. All samples taken from gymnasiums had significant levels of cat allergen only (above 0.1 µg/g dust)Conclusion: This study showed that any detectable level of cat allergen may be clinically significant. ER -