RT Journal Article SR Electronic T1 The PROactive instruments to measure physical activity in patients with chronic obstructive pulmonary disease JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP ERJ-01830-2014 DO 10.1183/09031936.00183014 A1 Elena Gimeno-Santos A1 Yogini Raste A1 Heleen Demeyer A1 Zafeiris Louvaris A1 Corina de Jong A1 Roberto A. Rabinovich A1 Nicholas S. Hopkinson A1 Michael I. Polkey A1 Ioannis Vogiatzis A1 Maggie Tabberer A1 Fabienne Dobbels A1 Nathalie Ivanoff A1 Willem I. de Boer A1 Thys van der Molen A1 Karoly Kulich A1 Ignasi Serra A1 Xavier Basagaña A1 Thierry Troosters A1 Milo A. Puhan A1 Niklas Karlsson A1 Judith Garcia-Aymerich YR 2015 UL http://erj.ersjournals.com/content/early/2015/05/28/09031936.00183014.abstract AB No current patient-centred instrument captures all dimensions of physical activity in chronic obstructive pulmonary disease (COPD). Our objective was item reduction and initial validation of two instruments to measure physical activity in COPD.Physical activity was assessed in a 6-week, randomised, two-way cross-over, multicentre study using PROactive draft questionnaires (daily and clinical visit versions) and two activity monitors. Item reduction followed an iterative process including classical and Rasch model analyses, and input from patients and clinical experts.236 COPD patients from five European centres were included. Results indicated the concept of physical activity in COPD had two domains, labelled “amount” and “difficulty”. After item reduction, the daily PROactive instrument comprised nine items and the clinical visit contained 14. Both demonstrated good model fit (person separation index >0.7). Confirmatory factor analysis supported the bidimensional structure. Both instruments had good internal consistency (Cronbach's α>0.8), test–retest reliability (intraclass correlation coefficient ≥0.9) and exhibited moderate-to-high correlations (r>0.6) with related constructs and very low correlations (r<0.3) with unrelated constructs, providing evidence for construct validity.Daily and clinical visit “PROactive physical activity in COPD” instruments are hybrid tools combining a short patient-reported outcome questionnaire and two activity monitor variables which provide simple, valid and reliable measures of physical activity in COPD patients.Both PROactive hybrid tools are simple, valid, and reliable measures of physical activity in COPD patients http://ow.ly/LJqP8