RT Journal Article SR Electronic T1 Anti-reflux surgery in lung transplant recipients: Outcomes and effects on quality of life JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP erj00618-2011 DO 10.1183/09031936.00061811 A1 A.G.N. Robertson A1 A. Krishnan A1 C. Ward A1 J.P. Pearson A1 T. Small A1 J. Lordan A1 P.A. Corris A1 J.H. Dark A1 D. Karat A1 J. Shenfine A1 S.M. Griffin YR 2011 UL http://erj.ersjournals.com/content/early/2011/08/04/09031936.00061811.abstract AB Fundoplication may improve survival post-lung transplant. Little is known on the effects of fundoplication on quality of life in these patients. The aim of this study was to assess safety of fundoplication in lung transplant recipients and its effects on quality of life. Between 1st June 2008 and 31st December 2010, a prospective study of lung transplant recipients undergoing fundoplication was undertaken. Quality of life was assessed before and after surgery. Body mass index and pulmonary function were followed up. Sixteen patients, mean age 38years (+/−11.9years), underwent laparoscopic Nissen fundoplication. There was no peri-operative mortality or major complications. Mean hospital stay was 2.6 days (+/−0.9days). 15/16 patients were satisfied with the results of surgery post fundoplication. There was a significant improvement in Reflux Symptom Index and DeMeester questionnaires and GIQLI scores at six months. Median BMI decreased significantly post-fundoplication (p=0.01). Patients operated on for deteriorating lung function had a statistically significant decrease in the rate of lung function decline post-fundoplication (p=0.008). Laparoscopic fundoplication is safe in selected lung transplant recipients. Patient benefit is suggested by improved symptoms and satisfaction. This procedure is acceptable, improves quality of life and may reduce deterioration of lung function.