PT  - JOURNAL ARTICLE
AU  - D. Ghosh
AU  - P. Rzehak
AU  - M. W Elliott
AU  - W. Windisch
TI  - Validation of the english severe respiratory insufficiency questionnaire
AID  - 10.1183/09031936.00152411
DP  - 2012 Jan 01
TA  - European Respiratory Journal
PG  - erj01524-2011
4099  - http://erj.ersjournals.com/content/early/2011/12/16/09031936.00152411.short
4100  - http://erj.ersjournals.com/content/early/2011/12/16/09031936.00152411.full
AB  - Assessment of health-related quality of life in patients with respiratory failure on home ventilation requires appropriate and highly specific measurement tool. We attempt to validate the English version of the Severe Respiratory Insufficiency Questionnaire (SRI).Psychometric properties of the SRI in 152 patients established on home ventilation were assessed.Cronbachs's Alpha reliability ranged between 0.77 and 0.89 for the seven subscales and was 0.93 for the summary scale. Principal components analysis revealed a one factor solution for four and two factors for three subscales. Confirmatory factor analysis revealed a two factor solution for six subscales, but these factors were dependent with each other. One factor was extracted out of the subscales confirming one summary scale accounting for 70% of the total variance. Correlation analysis between scales of the SRI and the MOS 36-item Short Form Health Survey demonstrated highest correlations between comparable subscales. COPD patients had lower summary scale scores than patients with restrictive chest wall diseases, neuromuscular disorders and obesity hypoventilation syndrome.The English SRI has high internal consistency reliability, clearly established construct and concurrent validity, and is capable of differentiating between different diseases. It is now validated for use in research involving patients receiving home ventilation.