RT Journal Article SR Electronic T1 A comparative study of two- versus one-lung ventilation: for needlescopic bleb resection JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP erj00568-2010 DO 10.1183/09031936.00056810 A1 H. Kim A1 H.K. Kim A1 D-Y. Kang A1 D-K. Lee A1 Y.H. Choi A1 S.H. Lim YR 2010 UL http://erj.ersjournals.com/content/early/2010/08/06/09031936.00056810.abstract AB This prospective study was conducted to evaluate the feasibility of two-lung ventilation with low tidal volume anaesthesia compared to one-lung ventilation used for needlescopic bleb resection.Patients with spontaneous pneumothorax that underwent bleb resection with a 2 mm thoracoscope were enrolled. During the operation, the tidal volume was set at 4.0 mL·kg−1 in the two-lung group and 8.0 mL·kg−1 in the one-lung group; the respiration rate was set at 23/min and 12/min, respectively, at the same FiO2 (50%).A total of 108 patients (55 patients in the two-lung group and 53 in the one-lung) were included in this study. The airway pressure was significantly lower in the two-lung group (8.0±3.3 mmHg, 24.0±3.9 in one-lung, p<0.001). The time from endotracheal intubation to the incision was 17.1±4.0 minutes in the two-lung group and 35.3±7.6 in the one-lung, significantly different (p<0.001). However, the operation time was not different in comparisons between the two groups. Therefore, the total anaesthesia time was significantly longer in the one-lung group (77.9±21.6 minutes, 64.9±14.7 in two-lung, p=0.002).Needlescopic bleb resection using two-lung ventilation anaesthesia with low tidal volume was technically feasible, cost effective and time saving compared to one-lung ventilation anaesthesia.