RT Journal Article SR Electronic T1 Validity of spirometry performed on-line JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP erj00115-2010 DO 10.1183/09031936.00011510 A1 J.F. Masa A1 M.T. González A1 R. Pereira A1 M. Mota A1 J.A. Riesco A1 J. Corral A1 J. Zamorano A1 M. Rubio A1 J. Teran A1 R. Farré YR 2010 UL http://erj.ersjournals.com/content/early/2010/07/22/09031936.00011510.abstract AB Spirometry is essential for the diagnosis and management of common respiratory diseases. However, its use and quality is low in primary care. An important reason is the technical difficulty in performing conventional spirometry. If high quality spirometry could be performed on-line, from the pulmonary function laboratory in hospitals, most of the technical problems could be solved.To compare spirometries performed on line by remote technicians with conventional spirometry.This was a controlled, randomized crossover study. Two hundred and sixty one patients referred from primary care centres for pulmonary consultation were the target population. They were randomized to begin with either conventional or on-line spirometries. The technician, located remotely, controlled the spirometer computer. Using a teleconference link, the technician guided the patient through the spirometry. The comparison between conventional and on line spirometries was performed on an “intention to treat” and “per protocol” basis for spirometric values and quality criteria. Agreement between the two spirometric methods was assessed with a Bland and Altman plot. A subpopulation of off-range patients was also characterized. Finally, intra- and inter-observer agreement was evaluated using the intraclass correlation coefficient.No clinically significant differences were seen between the on-line and conventional spirometric values in both the intention to treat and per protocol analyses. The agreement in Bland and Altman analysis was worse for intention to treat than for the per protocol analysis. The latter had a lower percentage of off-range patients, and high agreement to determine abnormal spirometry in off-range group. Conventional spirometry had a higher percentage of patients with spirometric quality criteria although the quality criteria difference was only 5.9%, when both procedures were the first to start. Very good agreement was found between intra and inter-observer reliability.Spirometry performed on-line from a hospital can be an adequate alternative to conventional spirometry for primary care centres.