TY - JOUR T1 - Anti-reflux surgery in lung transplant recipients: Outcomes and effects on quality of life JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/09031936.00061811 SP - erj00618-2011 AU - A.G.N. Robertson AU - A. Krishnan AU - C. Ward AU - J.P. Pearson AU - T. Small AU - P.A. Corris AU - J.H. Dark AU - D. Karat AU - J. Shenfine AU - S.M. Griffin Y1 - 2011/01/01 UR - http://erj.ersjournals.com/content/early/2011/07/12/09031936.00061811.abstract N2 - Fundoplication may improve survival post-lung transplant. Little is known on the effects of fundoplication on quality of life in these patients. The aim of this study was to assess safety of fundoplication in lung transplant recipients and its effects on quality of life. Between 1st June 2008 and 31st December 2010, a prospective study of lung transplant recipients undergoing fundoplication was undertaken. Quality of life was assessed before and after surgery. Body mass index and pulmonary function were followed up. Sixteen patients, mean age 38years (+/−11.9years), underwent laparoscopic Nissen fundoplication. There was no peri-operative mortality or major complications. Mean hospital stay was 2.6 days (+/−0.9days). 15/16 patients were satisfied with the results of surgery post fundoplication. There was a significant improvement in Reflux Symptom Index and DeMeester questionnaires and GIQLI scores at six months. Median BMI decreased significantly post-fundoplication (p=0.01). Patients operated on for deteriorating lung function had a statistically significant decrease in the rate of lung function decline post-fundoplication (p=0.008). Laparoscopic fundoplication is safe in selected lung transplant recipients. Patient benefit is suggested by improved symptoms and satisfaction. This procedure is acceptable, improves quality of life and may reduce deterioration of lung function. ER -